The human c-rel proto-oncogene (REL) encodes a nuclear factor (NF)-κB family transcription factor. Misregulated REL is associated with B-cell malignancies in several ways (Gilmore et al., 2004).
The distinct phenotypes of knockout mice lacking individual Rel/NF-κB family members and the different expression patterns of these proteins indicate that each family member has unique physiological ...
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