Human immunodeficiency virus (HIV)-infected individuals with latent Mycobacterium tuberculosis infection have substantially higher rates of progression to active tuberculosis than HIV-uninfected ...
La Jolla Institute for Immunology (LJI) is working to guide the development of new tuberculosis vaccines and drug therapies. "This research gives us a better understanding of T cell responses to ...
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide - and ...
LJI Research Assistant Professor Cecilia Lindestam Arlehamn, Ph.D., led the new research in collaboration with LJI Professors Bjoern Peters, Ph.D., and Alessandro Sette, Dr.Biol.Sci. LA JOLLA, CA—La ...
Tuberculosis is a serious health threat, and the efficacy of the BCG vaccine against tuberculosis diminishes in adulthood, making booster vaccines a realistic option. Mycobacterial DNA-binding protein ...
A study led by UT Southwestern Medical Center researchers has found that certain antibodies inhibit Mycobacterium ...
From the Seshadri Lab as a part of the Cancer Consortium Support Grant To uncover whether these DURTs were associated with resistance to TB following exposure, the researchers utilized their cohort of ...
Researchers from the University of Pittsburgh Center for Vaccine Research report that innate CD8+ lymphocytes are essential for curbing tuberculosis (TB) the disease. They also discovered that ...
Macrophages infected with Mycobacterium tuberculosis were fixed and imaged at four hours and 72 h postinfection. (Scale bar, 4 μm.) LAM labeling with oxaziridines persists for up to 72 h. Images are ...
Chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the world's deadliest pathogen. This labeling could lead to simpler, faster TB tests.