Magnetic resonance imaging (MRI) has transformed the understanding and management of multiple sclerosis (MS) by enabling non-invasive characterisation of central nervous system pathology. Conventional ...

A new PET imaging approach that measures synaptic density in the spinal cord provides a quantitative way to assess the brain's functional wiring in patients with multiple sclerosis. With this ...

Iron dysregulation contributes to MS progression through oxidative stress, ferroptosis, and immune activation, affecting neuronal and immune cell function. Both iron overload and deficiency exacerbate ...

The National Multiple Sclerosis Society has provided a grant to a Wayne State University School of Medicine professor to explore a new model of MS pathology. Alexander Gow, Ph.D., the Charles H.

Multiple sclerosis (MS) is the result of the immune system mistakenly attacking the brain and the spinal cord, causing tissue damage (lesions) throughout. While the underlying mechanism of lesion ...

More research is necessary to understand cerebral oxygen consumption as a predictive biomarker for brain atrophy in multiple sclerosis (MS); however, this study found that mitochondrial dysfunction ...

Collaborating scientists at the Karolinska Institute and at Stockholm University used a technology called in situ sequencing (ISS) to help reveal at the cellular level how lesions in multiple ...

A landmark study has uncovered novel ancestry-specific genetic variants linked to multiple sclerosis (MS), offering new insights that could reshape treatment approaches for diverse populations ...

Multiple sclerosis (MS) is a disorder that prompts the body's immune system to attack myelin, the protective sheath covering nerve cells in the brain, optic nerve and spinal cord. This can in turn ...