Merck and Moderna, melanoma
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Melanoma was slower to recur in patients receiving Merck and Moderna's mRNA vaccine with Keytruda, supporting use of the combination in adjuvant treatment. The partners plan to take the data to the FDA.
The Food and Drug Administration granted accelerated approval to Zenbexus, or iberdomide, in combination with daratumumab and hyaluronidase-fihj and dexamethasone for certain adults with previously treated multiple myeloma. The drug is made by Bristol Myers Squibb.
Moderna and Merck are advancing an experimental mRNA vaccine aimed at preventing melanoma — the deadliest form of skin cancer — from returning after surgery, with FDA approval sought for next year.
Investors had been pessimistic about the probability of success for the personalized cancer vaccine intismeran autogene, so the Phase 3 win was a welcome surprise.