Abstract. Most definitions of cancer broadly conform to the current NCI definition: “Cancer is a disease in which some of the body's cells grow uncontrollably and spread to other parts of the body.” ...
Abstract. Myeloid sarcoma, an aggressive extramedullary subtype of acute myeloid leukemia (AML), occurs in approximately 20% of patients, and remains strikingly understudied in large-scale genomic and ...
B7-H3 (CD276), an immune checkpoint member of the B7/CD28 family, is widely expressed in multiple cancers and is associated with poor prognosis. YL201 is a novel B7-H3-targeting antibody-drug ...
Mol Cancer Ther (2023) 22 (12_Supplement): PR008.
Cancer Res (2025) 85 (8_Supplement_2): CT012. Novel immune strategies are needed to improve outcomes in patients (pts) with microsatellite-stable metastatic colorectal cancer (MSS mCRC). Our ...
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Cancer Res (2025) 85 (8_Supplement_2): CT112.
Cancer Res (2025) 85 (8_Supplement_2): ND07. FAP (Fibroblast Activation Protein) is expressed on cancer-associated fibroblasts (CAFs) and is a highly attractive target in Radioligand Therapy (RLT) due ...
EGFR and HER3 are receptor tyrosine kinases that are highly expressed in multiple epithelial tumors. EGFR point mutations and small insertions within the kinase domain are common in lung cancer. HER3 ...
Cancer Discov (2026) 16 (8): OF1.
Abstract. Ladiratuzumab vedotin (LV, SGN-LIV1A) is an antibody-drug conjugate directed against the LIV-1 protein that is currently under investigation for treatment in metastatic breast cancer. This ...
Cancer Discov (2026) 16 (8): OF1.
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