We report a woman in her 20s with congenital adrenal hyperplasia (CAH) due to a clinical diagnosis of 11β-hydroxylase deficiency, bilateral ovarian adrenal rest tumours (OARTs), autoimmune Addison’s ...

A Southeast Asian woman in her 70s presented with a 15-month history of multiple violaceous non-pruritic, non-painful skin ...

A man in his early 30s presented with a 4-month history of low-grade fever and chronic dry cough. Three months before ...

Charcot joint arthropathy is a progressive degenerative condition where neuropathy causes joint destruction, deformity and ...

A healthy man in his 40s presented with acute anterolateral ST-segment elevation myocardial infarction after sudden-onset chest pain during a coughing episode. Coronary angiography and intravascular ...

Syphilis can present with diverse ocular manifestations, including optic nerve and retinal involvement, often mimicking inflammatory or demyelinating disorders. In patients with pre-existing ...

A man in his 70s with lung adenocarcinoma (cStage IVA) received POSEIDON-based therapy with durvalumab, tremelimumab and chemotherapy. After six cycles, progressive disease prompted a switch to ...

Henoch-Schönlein purpura (HSP) is a small vessel immunoglobulin A (IgA) vasculitis that primarily affects children.

A woman in her 40s presented with a 2-day history of progressive left lower limb swelling and dyspnoea. She had a background ...

Electrical storm (ES) following acute coronary syndrome is rare but often fatal. A man in his early 70s experienced syncope and dyspnoea while playing golf, approximately 2 weeks after experiencing ...

Macrolides are an essential component of non-tuberculous mycobacterium management and being labelled with an allergy can result in these medications being avoided despite them being the preferred ...

We report a boy in mid-childhood with previously undiagnosed vertically acquired HIV who presented with progressive developmental regression, language impairment, gait disturbance and pyramidal signs.