As we look forward, we envision that the focus of clinical cardiology at Circulation will remain centered on clinical impact, ...

Cardiomyocytes exhibit marked susceptibility to ferroptosis after myocardial infarction (MI), rendering ferroptosis inhibition a promising therapeutic strategy to mitigate ischemic myocardial injury.

Chagas disease (ChD), a neglected cardiovascular condition, affects 7.5 to 10.5 million people worldwide. Opportunistic screening during routine electrocardiography may allow earlier detection of ...

Mature mammalian cardiomyocytes (CMs) develop compact sarcomeric structures that inhibit proliferation. Consequently, CMs must dedifferentiate to a fetus-like state, which is accompanied by sarcomere ...

Explore the latest research and articles on cardiovascular health and disease in Circulation's current issue.

Pediatric heart failure–related cardiogenic shock carries high morbidity and mortality but is understudied. Improving outcomes in pediatric cardiogenic shock hinges on timely diagnosis and appropriate ...

A 58-year-old man with a history of obesity, hyperlipidemia, and anxiety was referred to the cerebrovascular clinic with intermittent dizziness when turning his head to the right. These symptoms ...

On page e955 and in Tables 18 and 19 on page e957, the subsequent references after new Reference 18 are renumbered as References 19 through 37. On page e1029, in “Appendix 2. Reviewer Relationships ...

A 27-year-old, previously healthy woman with no history of migraine presented to the emergency department with sudden-onset left hemiparesis. Her only stroke risk factor was oral contraceptive use for ...

In the article by Heidenreich et al, “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on ...

Introduction: The rising global burden of hypertension necessitates the identification of effective strategies for its control and prevention, complementing advancements in pharmacotherapy. The ...

Downregulation of ECHS1 was observed in human hearts with hypertrophic cardiomyopathy (Figure [B]). ECHS1 downregulation was coupled with the upregulation of H3K18cr and H2BK12cr (Figure [C]), ...