PharmiWeb

Merck Announces Late-Breaking Data from Three Phase 3 Trials Evaluating Doravirine/Islatravir (DOR/ISL), an Investigational, Once-Daily, Two-Drug Regimen for the Treatment of ...

INSTI, two-drug regimen to demonstrate non-inferiority and a similar safety profile at Week 48 to BIC/FTC/TAF in adults living with HIV-1 who had not previously received antiretroviral ...
Frontiers

NSAIDs Beyond COX in Infection: Innate Sensing, Resolution, and Biofilm vs Planktonic Outcomes

Non-steroidal anti-inflammatory drugs (NSAIDs) are classically defined by cyclooxygenase (COX) inhibition, yet increasing evidence shows that many NSAIDs ...
Cochrane

What are the risks and benefits of taking aspirin or other nonsteroidal anti-inflammatory medicines (NSAIDs) to prevent bowel cancer in the general population?

NSAIDs are a group of drugs that help reduce inflammation, fever, and pain, and can also help prevent blood clots. Aspirin and ibuprofen are examples of widely used NSAIDs. They have been studied as a ...
Frontiers

Neural Mechanisms of Exercise-Induced Pain Relief

BackgroundPhysical activity and exercise not only enhance physical fitness, mental health, and quality of life, but also play a critical role in preventing ...

Study compiles 30 years of adhesion GPCR modulators and their key concentrations

Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly expanding body of knowledge on the therapeutic targeting of these receptors ...