Merck and Moderna, melanoma
Digest more
Melanoma was slower to recur in patients receiving Merck and Moderna's mRNA vaccine with Keytruda, supporting use of the combination in adjuvant treatment. The partners plan to take the data to the FDA.
A single Phase 3 readout just shook the cancer treatment world, sending one biotech stock to its biggest single-day gain ever and forcing Wall Street to rethink whether personalized mRNA therapies have finally crossed the line from promising to proven.
The Food and Drug Administration granted accelerated approval to Zenbexus, or iberdomide, in combination with daratumumab and hyaluronidase-fihj and dexamethasone for certain adults with previously treated multiple myeloma. The drug is made by Bristol Myers Squibb.
Investors had been pessimistic about the probability of success for the personalized cancer vaccine intismeran autogene, so the Phase 3 win was a welcome surprise.