Who's playing? Who's injured? Check out the San Francisco 49ers' unofficial depth chart after preseason Week 1.

The San Francisco 49ers remain one of several teams monitoring the situation surrounding Tampa Bay Buccaneers defensive tackle Vita Vea, who requested a trade nearly three weeks ago after contract extension talks stalled.

Fueled by a boom in artificial intelligence, San Francisco is quickly becoming the hottest housing market in the country.

A cable problem shut down San Francisco's California Cable Car Line for the rest of Thursday night, capping a day of Muni delays, staffing shortages and an Embarcadero traffic-signal outage.

Tesla is planning 124-stall V4 Supercharger hub in San Francisco, significantly expanding public charging capacity in the city.

As thousands of San Francisco public school students prepare to return to class Monday, district leaders say they are entering the new school year with a balanced budget but still face long-term challenges tied to declining enrollment.

The Colorado Rockies open the final series of their nine-game road trip against a Giants team they have played nearly even all season and trail by just two games in the NL West.

Andon Labs, which is experimenting with letting an AI have majority control over a retail store, said that it fired an employee with good reason.