Gut

Rare cause of epigastric distension and vomiting

A 61-year-old Chinese female was admitted with a 1-week history of epigastric pain. She reported recurrent episodes of mild ...
GutOpinion

Deferring first surveillance to 3 years after colorectal ESD is not supported by these data

Qatomah and colleagues conclude that the first surveillance colonoscopy (SC1) after colorectal endoscopic submucosal ...
gut.bmj

Postoperative anatomy as a potential confounder in single-cell analyses of Lynch syndrome-associated colorectal cancer risk

We read with great interest the study by Yang and colleagues, who provide an important single-cell multiomic resource of tumour-free colonic mucosa from individuals with Lynch syndrome (LS), with and ...
Gut

Faecal proteases and immune signatures drive subtype-specific enteric neuronal activation in IBS

Background Luminal proteases have been implicated in epithelial barrier dysfunction and visceral hypersensitivity in ...
gut.bmj

Impact of initial severity and progression pattern of new-onset diabetes on pancreatic cancer risk: a 15-year longitudinal nationwide cohort study

Background New-onset diabetes (NOD) increases the risk of pancreatic cancer. Previous studies have mainly focused on the presence or absence of diabetes, with limited attention to NOD severity at ...
gut.bmj

Ustekinumab for fistulising perianal Crohn’s disease: a randomised placebo-controlled trial from the GETAID

Background Fistulising perianal Crohn’s disease (CD) remains a debilitating condition, with few randomised controlled trials conducted so far. Objective To evaluate the efficacy and safety of ...
gut.bmj

Conclusions in search of a confirmatory analysis: the evidence does not yet justify routine proton pump inhibitors after endoscopic variceal ligation

The trial by Yadav and colleagues concludes that proton pump inhibitors (PPIs) should be continued routinely after endoscopic variceal ligation (EVL).1 The data show a plausible directional signal of ...
gut.bmj

Deciphering the prodrome of inflammatory bowel disease up to 10 years before disease onset by massively parallel serology

Background Defining immune dysregulation during the asymptomatic prodrome of immune-mediated diseases offers opportunities for early disease detection and interception. In inflammatory bowel disease ...
gut.bmj

Should serotonin-noradrenaline reuptake inhibitors be considered the most effective neuromodulators for irritable bowel syndrome?

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...