Cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) is an adult-onset, slowly progressive neurodegenerative disorder characterised in its full form by cerebellar ataxia, sensory ...

Objective: To explore the profile of neuropsychiatric symptoms in patients with dementia associated with Parkinson’s disease (PDD). Methods: 537 patients with PDD drawn from an international ...

Background and purpose The prevalence of Huntington's disease (HD) in the UK is uncertain. Recently, it has been suggested that the prevalence may be substantially greater than previously reported.

a Department of Neurology, St Vincent’s Hospital, Elm Park, Dublin 4, Ireland, b Molecular Genetics, Division of Biomedical Sciences, Imperial College School of Medicine, South Kensington Campus, ...

a Department of Medicine (Neurology), University of Wales College of Medicine, Cardiff, UK, b The Common Cold Centre, Cardiff School of Biosciences, Cardiff University, UK Dr S Hadjikoutis, Department ...

Tremor is one of the clinical manifestations of dystonia; however, there are no specific therapeutic trials evaluating the efficacy of treatments for dystonic tremor (DT), tremor associated with ...

Centre for PET, Austin Health, Melbourne and Colin L Masters, Department of Pathology, University of Melbourne, Australia Background: Neuropathological studies have reported varying amounts of amyloid ...

Background: The visual association test (VAT) is a brief learning task based on imagery mnemonics. The test materials consist of six line drawings of pairs of interacting objects or animals—for ...

Background In the CLARITY AD study, lecanemab was shown to reduce markers of amyloid and slow cognitive decline at 18 months in early Alzheimer’s disease (AD). Here, we report the initial findings ...

Objective: To study the safety and efficacy of the cholinesterase inhibitor donepezil in patients with Parkinson's disease (PD) and cognitive impairment. Methods: This was a double blind, randomised ...

1 Academic Neurology Unit, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK 2 Department of Liaison Psychiatry, Brandon Mental Health Unit, Leicester General ...

Background Hereditary transthyretin amyloidosis (ATTR) is usually characterised by a progressive peripheral and autonomic neuropathy often with associated cardiac failure and is due to dominantly ...