We are back for Day 2 of the 2026 Milton Wexler Biennial Symposium in Boston, Massachusetts, with the Huntington’s Disease Foundation. Today’s scientific talks covered a range of topics, from somatic ...

As with other shared clinical datasets, participant identities remain protected through secure coding and anonymisation.

Roche’s news also reminds us of a broader challenge. Many of today’s genetic therapies are scientifically remarkable, but ...

8 min read | July was a hard month for Huntington’s disease research, with Roche ending two HD programs. But the month also brought promising new tools, a new player in somatic expansion, and ...

Huntington’s disease (HD) is caused by a change in a single gene known as huntingtin. This gene contains the instructions for making the huntingtin proteinhuntingtin protein The protein produced by ...

Today, Roche announced in a community letter difficult news for the Huntington’s disease (HD) community, discontinuing two separate clinical programmes after new data emerged from ongoing studies. The ...

In plain language. Written by scientists. #Buzzilia, day 4: Jeff and Ed's roundup of happenings from the closing day of the HD World Congress in Rio de Janeiro #Buzzilia, day 3: Jeff and Ed's roundup ...

Huntington’s disease (HD) involves the loss of cells in the striatum, an area of the brain that plays important roles in movement, cognition, and behaviour. For decades, researchers have been ...

A recent collaboration between researchers at the University of Leiden and the Huntington Expertise Center Topaz Overduin in the Netherlands has focused on an important yet often overlooked part of ...

A new study shows that lowering a harmful piece of the huntingtin message (Htt1a) appears effective at reducing HD-related symptoms in mice, perhaps more so than targeting full length HTTHTT one ...

⏱️ 5 min read | A recent study suggests that strengthening the brain’s own clean-up system could slow Huntington’s disease. Cells in our body have a trash-disposal system to remove any damaged or ...

On April 30, 2026, uniQure announced that it held a Pre-Submission Meeting with the United Kingdom’s Medicines and Healthcare products Regulatory Agency (MHRA) and plans to file a formal application ...