We read with great interest the study by Yang and colleagues, who provide an important single-cell multiomic resource of tumour-free colonic mucosa from individuals with Lynch syndrome (LS), with and ...
A 61-year-old Chinese female was admitted with a 1-week history of epigastric pain. She reported recurrent episodes of mild ...
Background Luminal proteases have been implicated in epithelial barrier dysfunction and visceral hypersensitivity in ...
Qatomah and colleagues conclude that the first surveillance colonoscopy (SC1) after colorectal endoscopic submucosal ...
Background The liver naturally exhibits robust glycosylation processes, yet how aberrant glycosylation affects hepatocellular carcinoma (HCC) and its underlying mechanisms remains poorly understood.
Background Fistulising perianal Crohn’s disease (CD) remains a debilitating condition, with few randomised controlled trials conducted so far. Objective To evaluate the efficacy and safety of ...
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Background Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction, with some recommended treatments targeting brain-gut axis dysfunction. Objective To compare relative efficacy of ...
Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with high risk of surgery. Despite advances in medical treatment, of those patients who undergo ileocolonic ...
A 2-month-old male infant was admitted with a 2-day history of cough and fever. Respiratory pathogen testing on admission confirmed influenza A (H1N1) virus infection. The patient was started on oral ...
Background The optimal timing of endoscopic retrograde cholangiopancreatography (ERCP) in patients with mild-to-moderate acute cholangitis remains uncertain. Objective To compare the clinical outcomes ...