Pemafibrate improved cholestatic indices in a baseline-dependent fashion, irrespective of primary biliary cholangitis (PBC) status, supporting a mechanism that extends beyond disease-specific ...

Compared with non-survivors, survivors had lower N-terminal pro–B-type natriuretic peptide levels and a lower left ventricular mass index, along with a higher estimated glomerular filtration rate.

Chronotropic incompetence was associated with notably impaired functional capacity, such as lower peak oxygen uptake and decreased ventilatory efficiency. Chronotropic incompetence, in which the heart ...

For the primary composite outcome of all-cause mortality and recurrent cardiovascular events, vutrisiran showed consistent treatment benefit in both women and men, with hazard ratios of 0.59 and 0.71, ...