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alternativetomeds.com
Depakote Withdrawal Symptoms, Valproic Acid Side Effects, Treatment Help
Help withdrawing from Depakote, support for quitting, stopping, or discontinuing Valproic Acid divalproex sodium.
Mar 20, 2024
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#Valproate Mechanism of Action
Epilepsy (Generalized Tonic–Clonic Seizures) – Drug of Choice Tab. Sodium Valproate 500 mg PO BD Dose: Start 10–15 mg/kg/day, increase to 20–30 mg/kg/day in divided doses. Uses First-line drug for generalized tonic–clonic seizures. Also useful in myoclonic and absence seizures. Mechanism of Action ↑ GABA levels → enhances inhibitory transmission. Blocks voltage-gated sodium channels → stabilizes neuronal membranes. Blocks T-type calcium channels → suppresses abnormal discharges. Prescription Tab
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